For the full beer effect, you can visit during the annual Brewer's Weekend or stay anytime with the "Ales at the Inn" package (your night's stay comes with a pour, a bottle and a commemorative glass by which to remember it all).
Norwich Inn, 325 Main St., Norwich, Vermont; 802-649-1143; from $169 per night
The Lodge at Woodloch, Hawley, Pennsylvania
In what may be a first for both the wellness and craft beer industries, this globally recognized spa and resort has rolled out a series of suds-inspired spa treatments that blend stress remedies with ingredients from beers made by one of the East Coast's top breweries.
In addition to standard body scrubs, massages, facials and salon services offered at this lavish spa set on 70 acres in eastern Pennsylvania's Pocono Mountains, there's now a special package of treatments created in collaboration with the owner of Dogfish Head Brewery in nearby Delaware.
Visitors can stay in one of the Lodge's veranda suites or a neighboring family friendly resort, with spa options including the Royal Revival (a hops, barley and honey exfoliation, plus beer bath inspired by Dogfish Head's Midas Touch ale) or the Mud and Suds Pedicure, a beer foot soak paired with a glass of its muse brew, Palo Santo.
The Lodge at Woodloch, 109 River Birch Lane, Hawley, Pennsylvania; 570-685-8500; from $299 per night
The Brewery Creek Inn, Mineral Point, Wisconsin
In the 150 years since Cornish lead and zinc miners fled Mineral Point in search of California gold, cheap rents and peaceful surroundings have made the place a haven for artists and craftsmen.
So when Minneapolis expats Jeff and Deb Donaghue launched their Brewery Creek project in 1998, they allowed themselves some creative room, with three businesses in mind.
First is the Brewery Creek Inn, which occupies two restored cottages on historic Shake Rag Street and five rooms in a converted 1850s limestone warehouse off the town's main drag.
Second is Brewery Creek Brewing Co., a craft brewery located in one of the inn's buildings.
Third is the Brewery Creek pub and restaurant, a local watering hole and almost year-round kitchen that serves seasonal brews and fare.
Equal parts small town B&B and living history museum, Brewery Creek offers do-it-yourself room service and a brewery that churns out nothing but European beer styles (biere de garde, Scottish porter, dunkelweiss), allowing visitors to experience this quaint pre-Civil War town with a cold one in hand.
Brewery Creek Inn, 23 Commerce St., Mineral Point, Wisconsin; 608-987-3298; from $149 per night
Fredericksburg Brewing Co., Fredericksburg, Texas
The oldest brewpub in Texas is also the state's first B3, a term coined by vacationing beer geeks who noticed a growing number of B&Bs with attached breweries.
Fredericksburg Brewing Co. likes to call its invention a "bed and brew" -- 11 individually styled rooms poised just above the restaurant, a night's stay that entitles you to four free samples of house-made beer.
Though other breweries have since moved into this Hill Country town, this German-inspired B3 maintains a top-notch beer selection with a helles lager, porter and red ale that consistently garner medals at national and international competitions.
After a night in the Admiral's Quarters or Cowboy Room, you can stay cool in the brewpub's climate controlled beer garden or browse historic downtown Fredericksburg -- where sidewalk consumption is legal -- while knocking back a fresh beer.
Fredericksburg Brewing Co., 245 E. Main St., Fredericksburg, Texas; 830-997-1646; from $129 per night
Saratoga Resort and Spa/Snowy Mountain Brewery, Saratoga, Wyoming
What the tiny city of Saratoga lacks in population it makes up for in locally made beer.
Buried inside the massive Saratoga Resort and Spa is the Snowy Mountain Brewery, one of the oldest brewpub operations in the state.
In 2009, after a several year hiatus, during which its brewing equipment lay dormant, the resort's owners hired brewmaster Steve Simpson. It has since maintained a steady tap list of nine house beers, from Saratoga witbier to Citra IPA.