WASHINGTON -

Federal agents are serving hundreds of warrants in dozens of cities, including Orlando, as part of a continued crackdown on synthetic drug manufacturers, wholesalers and retailers.

The Drug Enforcement Administration says agents in at least 25 states began serving search and arrest warrants Wednesday at homes, warehouses and smoke shops.

Walsh says warrants were served at Milano Jewelers in the Altamonte Mall, a home in the 12000 block of McKinnon Road in Windermere and a warehouse in the 3400 block of Orlando.

The largest single operation is a statewide effort in Alabama. Agents also are serving warrants in New Mexico, among other states.

Rusty Payne of the DEA says the latest crackdown involves 33 DEA cases, and seven investigations led by Immigration and Customs Enforcement agents.

Customs and Border Protection is also working on several cases involving express consignment shipments.