All-Pro Matthew Stafford rallied the Rams to a victory at Carolina last week to set up a divisional round matchup at Chicago on Sunday.

Brock Purdy threw a 4-yard touchdown pass to Christian McCaffrey, leading San Francisco to a 23-19 victory over defending Super Bowl champion Philadelphia in a wild-card game.

Brock Purdy threw a 38-yard touchdown pass to Jauan Jennings with 2:15 to play, and the San Francisco 49ers forced an incomplete pass on the final play from the 2 to beat the Chicago Bears 42-38 and set up a Week 18 showdown for the top seed in the NFC.

Brock Purdy threw a career-high five touchdown passes and Dee Winters returned an interception 74 yards for a score to lead the San Francisco 49ers to a 48-27 victory at Indianapolis.

Carolina Panthers safety Tre’von Moehrig has been suspended one game without pay for punching San Francisco 49ers wide receiver Jauan Jennings in the groin during Monday’s game.

San Francisco receiver Jauan Jennings responded to a cheap shot from Carolina safety Tre'Von Moehrig by throwing a punch after the final whistle.

Christian McCaffrey had a big night in his first game against Carolina since the Panthers traded him to San Francisco three years ago.

Four-time All-Pro linebacker Fred Warner will need season-ending surgery after he was sidelined by a severe ankle injury during San Francisco's loss to Tampa Bay.

Mac Jones is becoming the latest quarterback to prove he was dumped too soon.

San Francisco star defensive end Nick Bosa tore the ACL in his right knee and will miss the rest of the season.

Quarterback Brock Purdy is highly unlikely to start for the San Francisco 49ers on Sunday because of a toe injury.

San Francisco 49ers quarterback Brock Purdy is a "long shot" to play against the New Orleans Saints on Sunday due to a toe injury.

San Francisco 49ers star Christian McCaffrey is questionable for the season opener after injuring his calf at practice.

Christian McCaffrey has been a standout at the San Francisco 49ers' training camp, remaining healthy after missing most of last season because of injuries.

The San Francisco 49ers have agreed to acquire receiver Skyy Moore from the Kansas City Chiefs.

The San Francisco 49ers have given receiver Deebo Samuel permission to seek a trade, according to a person familiar with the situation.

Deebo Samuel called for the ball more often this week on social media.

Joshua Karty hit a 37-yard field goal with 2 seconds to play, and the Los Angeles Rams staged a spectacular late rally for a 27-24 victory over the San Francisco 49ers.

Jauan Jennings’ historic Super Bowl milestone will turn into only a footnote after his San Francisco 49ers lost the game.

Jimmy Garoppolo threw one touchdown pass and ran in for a score, leading the San Francisco 49ers to a 17-11 victory over the Philadelphia Eagles.