The bowl game, which has raised more than $6.3 million for cancer research over its 10-year history, holds special meaning for many participants, past and present.

Official announced the matchups for all three bowl games being played in Orlando on Sunday afternoon with some heavy hitters coming to Camping World Stadium.

This year's StaffDNA Cure Bowl features Jax State and Ohio and will have News 6's own sports director Jamie Seh on the radio broadcast.

The game, which kicks off at noon on Dec. 20, will be played at Camping World Stadium.