DAVID BLOUGH

Brock Purdy led the San Francisco 49ers to their 10th consecutive win to end the regular season on the highest of notes against the Arizona Cardinals.

SANTA CLARA, Calif. — (AP) — Brock Purdy threw three touchdown passes for his sixth straight game with multiple TDs and the San Francisco 49ers clinched the No. The Cardinals (4-13) ended the season going in the opposite direction with seven straight losses to tie a franchise record for losses in a season. The game started well for Arizona when fourth-string quarterback David Blough connected on a 77-yard TD pass to A.J. Green off a trick play on the second play from scrimmage. The two connected again late in the third quarter, giving Kittle seven TD catches from Purdy in the last four games.

Mitch Trubisky staked his claim to be the Pittsburgh Steelers starting quarterback, throwing for 160 yards and a touchdown in a 19-9 win over Detroit in the NFL's preseason finale.

This was a good week for us.”Igwebuike had a solid game, carrying seven times for 32 yards, including his strong final run. But Blough wanted to show everyone he could rebound from last week's late turnover, which turned an almost sure win into another frustrating defeat. Boyle took over in the second half and led the Lions to two touchdowns. ... Craig Reynolds started at running back and had seven carries for 37 yards including back-to-back 11-yard runs in the first half. Colts: Linebacker Brandon King left the game in the first half with a hamstring injury and did not return.

Godwin Igwebuike's tiebreaking 2-yard run with 4:03 left led the Detroit Lions to a 27-26 victory at Indianapolis.

Jake Fromm threw a 42-yard, fourth-down pass to rookie Marquez Stevenson to set up Tyler Bass’ 44-yard field goal with 15 seconds left in the Buffalo Bills’ 16-15 victory over the Detroit Lions on Friday night.

Tampa Bay Buccaneers quarterback Tom Brady (12) throws during the first half of an NFL football game against the Detroit Lions, Saturday, Dec. 26, 2020, in Detroit. The Bucs (10-5) set a franchise record with 588 yards and snapped the NFL’s second-longest postseason drought behind Cleveland’s 18-year run that can end Sunday. “We’ve been scratching and clawing every single year to make the tournament," said receiver Mike Evans, who was drafted by Tampa Bay six years ago. Tampa Bay rested Brady ahead 34-0, its largest halftime lead in franchise history. Tampa Bay set team records in points (34) and yards (410) in the first half.

(AP Photo/Aaron Doster)The New York Giants will be without starting quarterback Daniel Jones for Sunday’s game against the Seattle Seahawks. Jones was not expected to play because of a hamstring injury suffered last week against Cincinnati. Colt McCoy will make his first start of the season at QB for the Giants. Seattle was without both starting right tackle Brandon Shell (ankle) and backup Cedric Ogbuehi (calf) leaving a major question on the offensive line. ___CLEVELAND-TENNESSEEBrowns: WR Taywan Taylor, WR KhaDarel Hodge, CB Denzel Ward, RB Dontrell Hilliard, S Tedric Thompson, DE Joe Jackson.

The unbeaten Pittsburgh Steelers wound up relatively healthy for their game against the AFC North rival Cincinnati Bengals following a brush with the novel coronavirus. Defensive tackle Tyson Alualu is also back after missing a game with a knee injury. Cincinnati is without running back Joe Mixon, whose lingering foot injury is forcing him to miss a third game in a row. Receiver Cooper Kupp, left tackle Andrew Whitworth and running back Darrell Henderson all were active after missing practices with injuries. Raiders: T Kolton Miller (ankle), DT Maurice Hurst (ankle), QB Marcus Mariota, RB Theo Riddick, G John Simpson, DT Daniel Ross.

DETROIT – Detroit Lions quarterback Matthew Stafford was placed on the Reserve/COVID-19 list, the second straight day the team gave a player the designation. Earlier in the day, Matt Patricia said there was no requirement to shut down the team’s training facility. Some NFL teams have closed their training centers after players and or staff members tested positive for COVID-19. Three months ago, the Lions removed Stafford from the COVID-19 list after saying he received a false positive test result. Kelly Stafford had plenty to say on her Instagram page in August after the false positive test, lashing out at the league for publicly putting her husband on the list.

(AP Photo/John Froschauer)Denver Broncos running back Phillip Lindsay has cleared concussion protocol and will play against the Los Angeles Chargers. Bears: WR Ted Ginn Jr., DB Duke Shelley, RB Artavis Pierce, OL Cody Whitehair, WR Riley Ridley, LB Trevis Gipson. Seahawks: RB Chris Carson, RB Carlos Hyde, DE Benson Mayowa, CB Ugo Amadi, SS Jamal Adams, CB Shaquill Griffin. ___LOS ANGELES RAMS AT MIAMIRams: RB Raymond Calais, OL Brian Allen, WR Trishton Jackson, TE Brycen Hopkins, DL A’Shawn Robinson. Dolphins: RB/WR Lynn Bowden Jr., RB Salvon Ahmed, FB Chandler Cox, CB Jamal Perry, RB Jordan Howard, DE Jason Strowbridge.

Titans: CB Joshua Kalu, LB Derick Roberson, LB David Long Jr., OL Daniel Munyer, T Isaiah Wilson, DL Matt Dickerson. Washington: T Geron Christian, WR Isaiah Wright, DE James Smith Williams, WR Robert Foster, LB Thomas Davis, DE Casey Toohill. ___DETROIT AT ATLANTALions: QB David Blough, CB Desmond Trufant, S Miles Killebrew, OL Logan Stenberg, WR Quintez Cephus, RB Bo Scarbrough. ___GREEN BAY AT HOUSTONPackers: QB Jordan Love, CB Kevin King, S Darnell Savage, RB Tyler Ervin, RB Aaron Jones, T David Bakhtiari, DL Tyler Lancaster. Texans: WR Keke Coutee, CB John Reid, LB Peter Kalambayi, T Charlie Heck, TE Jordan Akins.

___GREEN BAY AT TAMPA BAYPackers: RB Tyler Ervin, CB Kevin King, QB Jordan Love. ___NEW YORK JETS AT MIAMIJets: QB James Morgan, QB Sam Darnold, CB Quincy Wilson, LB Jordan Willis, T Mekhi Becton, DL Nathan Shepherd. Dolphins: B/WR Malcolm Perry, RB Salvon Ahmed, RB Jordan Howard, LB Kyle Van Noy, DE Jason Strowbridge. ___HOUSTON AT TENNESSEETexans: WR Keke Coutee, CB Cornell Armstrong, RB Buddy Howell, ILB Peter Kalambayi, OT Charlie Heck, TE Jordan Akins. ___ATLANTA AT MINNESOTAFalcons: CB Jordan Miller, RB Qadree Ollison, S Jaylinn Hawkins, RT John Wetzel, DE Takk McKinley.