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Jack Nunge scored 18 points, Adam Kunkel added 15 on five first-half 3-pointers, and No. 3 seed Xavier beat 11th-seeded Pittsburgh 84-73 to reach its first Sweet 16 since 2017.
Nelly Cummings scored 13 points and No. 11 seed Pittsburgh held sixth-seeded Iowa State to 23% shooting in a 59-41 victory in the first round of the NCAA Tournament.
Jamarius Burton made a go-ahead jumper with 10 seconds left and Pitt edged Mississippi State 60-59 in a back-and-forth First Four game that featured 21 lead changes — most in the NCAA Tournament in five years.