KEN AULETTA

Elizabeth Holmes once seemed destined to fulfill her dream of becoming Silicon Valley's next superstar.

That pledge is now a distant memory as Google confronts an existential threat similar to what Microsoft once faced. They focused on creating a database of everything on the internet through a search engine that almost instantaneously listed a pecking order of websites most likely to have what anyone wanted. Google's promotion of Chrome on its search engine helped the browser supplant Explorer as the market leader. Google began reining in its spending and even created a new holding company, Alphabet, to oversee some of its unprofitable projects, such as internet=beaming balloons and self-driving cars. —-Liedtke first interviewed Larry Page and Sergey Brin in 2000 when he began covering Google for the AP.