The ground-oriented, weather-proof offense has long been preferred by Big Ten teams.

Jimmy Garoppolo threw one touchdown pass and ran in for a score, leading the San Francisco 49ers to a 17-11 victory over the Philadelphia Eagles.

Rookie running back Elijah Mitchell, a sixth-round pick, had a 38-yard, tiebreaking touchdown in the second quarter to put the Niners ahead 14-7. The Tennessee Titans’ va...