The Florida Highway Patrol said an 18-year-old man is dead after a crash in the Doctor Phillips area around 8 p.m. on Sunday.
Investigators said Javier Thacker was a passenger in a 2004 Acura.
Fransico Suarez, 18, of Mount Dora, who was driving the Acura is in critical condition at Orlando Health.
FHP said Suarez was driving northbound on Turkey Lake Road and a 36-year-old man from Frankfurt, Germany was driving a 2019 Volvo southbound on Turkey Lake Road.
Suarez lost control of the Acura and struck a curb, according to FHP.
The Acura traveled into the southbound lanes, according to investigators.
Investigators said the front of the Volvo hit the right side of the Acura.
The crash is under investigation.