I-4 reopens in Orange County after crash leaves 5 hospitalized Crash happened near SR-528 around 4 p.m.
Traffic being rerouted along I-4 on Monday, Sept. 29 (Copyright 2025 by WKMG ClickOrlando - All rights reserved.)
ORANGE COUNTY, Fla. – A section of Interstate 4 has reopened on Monday evening after a box truck rolled over on the highway, according to the Florida Highway Patrol.
In a release, troopers said the crash happened in the eastbound lanes of I-4 near State Road 528 around 4 p.m.
Troopers said the roadblock was cleared around 7:30 p.m.
“It appears it could possibly be two separate crashes at this location,” an FHP spokesperson told News 6. “Preliminary evidence shows there were five transports to local hospital. One of the vehicles involved is a semi that overturned.”
An overturned box truck was spotted along I-4 on Monday, Sept. 29 (Copyright 2025 by WKMG ClickOrlando - All rights reserved.) No additional information about the crash has been provided at this time.
Breaking News Alerts Get breaking news alerts delivered to your inbox.
Copyright 2025 by WKMG ClickOrlando - All rights reserved.
About the Author Anthony Talcott headshot
Anthony, a graduate of the University of Florida, joined ClickOrlando.com in April 2022.
Protecting Florida’s Brown Pelicans: A collaborative effort to preserve a coastal icon ▶ 1:37
Protecting Florida’s Brown Pelicans: A collaborative effort to preserve a coastal icon
Don Lemon Arrest: Laws, Liberty and the Slippery Slope ▶ 0:49
Don Lemon Arrest: Laws, Liberty and the Slippery Slope
Volusia couple awaits FEMA help years after Hurricane Ian damaged home. Here’s why it’s taking so long ▶ 0:36
Volusia couple awaits FEMA help years after Hurricane Ian damaged home. Here’s why it’s taking so long
New video shows arrest of man accused in sex attack on Seminole Wekiva Trail ▶ 0:41
New video shows arrest of man accused in sex attack on Seminole Wekiva Trail
Federal judge declines to release immigrant detainee held at Orange Co. Jail for nearly 30 days ▶ 2:07
Federal judge declines to release immigrant detainee held at Orange Co. Jail for nearly 30 days
Preserving the legacy of Winter Park’s historic Black neighborhood in Hannibal Square ▶ 1:12
Preserving the legacy of Winter Park’s historic Black neighborhood in Hannibal Square
Video shows Marion County teen setting his friend on fire, deputies say ▶ 0:44
Video shows Marion County teen setting his friend on fire, deputies say
Volusia County considers ballot ban on toilet to tap water amid growing concerns ▶ 0:39
Volusia County considers ballot ban on toilet to tap water amid growing concerns
‘Inbred s***hole:’ Winter Park football coach investigated for profanity-laced message ▶ 1:08
‘Inbred s***hole:’ Winter Park football coach investigated for profanity-laced message
Orlando installing fencing at Pulse site ahead of demolition ▶ 0:56
Orlando installing fencing at Pulse site ahead of demolition
‘Hell of a day:’ Texts reveal state inspectors’ response to Universal roller coaster death ▶ 0:42
‘Hell of a day:’ Texts reveal state inspectors’ response to Universal roller coaster death
Politically Motivated: How Florida’s recreational marijuana amendment failed to make the 2026 ballot ▶ 0:56
Politically Motivated: How Florida’s recreational marijuana amendment failed to make the 2026 ballot
Orlando therapist community mourns loss of colleague stabbed to death, faces safety concerns ▶ 1:30
Orlando therapist community mourns loss of colleague stabbed to death, faces safety concerns
Orange County ‘following up on complaints’ about jail, as ICE holds surge ▶ 1:10
Orange County ‘following up on complaints’ about jail, as ICE holds surge
Day 2 of fiery protests ahead of another heated Town Hall for Fl. Rep. Cory Mills ▶ 0:45
Day 2 of fiery protests ahead of another heated Town Hall for Fl. Rep. Cory Mills
Residents to raise more concerns over proposal to let rocket wastewater into Indian River Lagoon ▶ 0:59
Residents to raise more concerns over proposal to let rocket wastewater into Indian River Lagoon
How do Florida alligators cope in cold weather? ▶ 1:18
How do Florida alligators cope in cold weather?
After 13 incredible years, Justin Warmoth is saying goodbye to News 6. ▶ 1:54
After 13 incredible years, Justin Warmoth is saying goodbye to News 6.
‘Im horrified:’ More Merritt Island neighbors speak against proposed LNG plant near homes ▶ 0:56
‘Im horrified:’ More Merritt Island neighbors speak against proposed LNG plant near homes
Orlando Volunteers Call for Better Care for Lake Eola Swans Amid Bird Flu Concerns ▶ 0:56
Orlando Volunteers Call for Better Care for Lake Eola Swans Amid Bird Flu Concerns
Teen to be arrested after Deltona dog killed in viral door kick-in challenge ▶ 0:57
Teen to be arrested after Deltona dog killed in viral door kick-in challenge
What the Florida?!?! Long stretch of winter weather invades Central Florida ▶ 1:28
What the Florida?!?! Long stretch of winter weather invades Central Florida
‘Inadvertently overlooked:’ Disabled veteran’s van towed at Orlando International Airport ▶ 1:07
‘Inadvertently overlooked:’ Disabled veteran’s van towed at Orlando International Airport
Sanford police seek ‘Peeping Tom’ accused of peering into home with blanket ▶ 0:31
Sanford police seek ‘Peeping Tom’ accused of peering into home with blanket
Rockledge man 3D printed gun parts only as a hobby, attorney says ▶ 1:04
Rockledge man 3D printed gun parts only as a hobby, attorney says
Previous photo Next photo 