Osceola quarterback Braxton Jones needed just two possessions against Oviedo to show off his versatility.
The Kowboys, playing their home opener, scored on its first drive of the game behind Jones' quarterback keeper that went for more than 25 yards.
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Jones capped off Osceola's next series with a touchdown throw to Fil Wynter.
The Kowboys hosts Kissimmee-area rival Liberty in Week 3.
Oviedo travels to its crosstown rival Hagerty.